Epigenetic services using Next Generation Sequencing
Epigenetics research focuses on biological or chemical influences that can change the expression of a gene. “Epi” is greek for “above or outside”, referring to the modifications such as methylation or hydroxymethylation that are attached to the DNA strands. Because the various epigenetic groups have different effects on the gene transcription, measuring these specific groups is important when explaining various (disease) phenotypes.
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Next Level Epigenetics with Oxford Nanopore Technologies
Epigenetics is crucial for regulating gene expression and is linked to various diseases, including cancer.
This approach is especially beneficial for detecting differentially methylated regions (DMRs), providing a comprehensive perspective on methylation patterns throughout extensive and intricate genomic areas.
Advantages:
- Detect base modifications alongside nucleotide sequence as standard with direct sequencing of native DNA and RNA.
- Epigenetics and genomics data in just one run.
- PCR-free.
- No additional sample preparation required.
Let's get the conversation started for your next NGS project
Please either fill in this form or email us directly at info@genomescan.nl
and we will get in touch with you to discuss your requirements.